Harper A P, Jackson V P, Bies J, Ransburg R, Kelly-Fry E, Noe J S
Ultrasound Med Biol. 1982;8(4):365-8. doi: 10.1016/s0301-5629(82)80003-3.
Thirty correctly diagnosed carcinomas were chosen for retrospective analysis of their ultrasound and X-ray imaging characteristics, and correlated with pathologic examination. It was determined that the ultrasound image correlated will with that revealed by radiographic techniques. The posterior attenuation shadow and the jagged wall were the prime indicators of malignancy in this study, occurring in 90 and 87% of the cases, respectively. However, in about 67% of these masses, attenuation shadowing was revealed only by close-interval (1mm) stepwise scanning. A nonhomogeneous internal echo pattern was found in 73% of the cases. Thirteen of the 30 masses showed disturbed architecture away from the overt lesion when imaged by ultrasound techniques. Seventy per cent of these showed histological abnormalities in remote regions. Finally, it was shown that the attenuation shadowing exhibited by malignant breast masses is related to the collagen content of the lesion, expressed as fibrosis.
选取30例经正确诊断的癌进行回顾性分析，研究其超声和X线影像特征，并与病理检查结果进行对比。结果表明，超声图像与放射技术所显示的图像具有良好的相关性。在本研究中，后方衰减阴影和边缘不整齐的壁是恶性肿瘤的主要指标，分别出现在90%和87%的病例中。然而，在这些肿块中，约67%的病例仅通过间隔紧密（1毫米）的逐步扫描才能显示出衰减阴影。73%的病例中发现内部回声不均匀。30个肿块中有13个在超声检查时显示远离明显病变处的结构紊乱。其中70%在远处区域显示出组织学异常。最后发现，恶性乳腺肿块所呈现的衰减阴影与病变的胶原含量有关，表现为纤维化。
