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蒽林与紫外线对银屑病的一小时治疗(作者译)

[One-hour-treatment of psoriasis with anthralin and UV-light (author's transl)].

作者信息

Schauder S, Mahrle G

出版信息

Z Hautkr. 1982 Jun 15;57(12):861-6.

PMID:7113317
Abstract

A total of 66 patients with psoriasis was treated with one percent anthralin for one hour (one-hour-treatment) and UV-light. 17 out of 26 out-patients treated with anthralin and UVB showed a good response. In 40 in-patients the one hour regimen was administered in combination with UVA or UVB, in part in right-left side comparison in order to evaluate whether anthralin with UV-light is more effective than anthralin alone. Within six weeks remission was obtained with anthralin alone as well as with combined treatment with anthralin and UVA or UVB. In right-left side comparison UV-light had no significant additional effect in this regimen. The one-hour-treatment was effective but did not seem to be superior to the conventional therapy with anthralin in in-patients. However, the one-hour-treatment is advantageous and convenient for out-patients.

摘要

共有66例银屑病患者接受了1%蒽林治疗1小时(1小时治疗)及紫外线照射。26例接受蒽林和UVB治疗的门诊患者中有17例反应良好。40例住院患者采用1小时治疗方案联合UVA或UVB,部分患者进行左右侧对照,以评估蒽林与紫外线联合治疗是否比单独使用蒽林更有效。在六周内,单独使用蒽林以及蒽林与UVA或UVB联合治疗均获得了缓解。在左右侧对照中,紫外线在该治疗方案中没有显著的额外效果。1小时治疗有效,但在住院患者中似乎并不优于传统的蒽林治疗。然而,1小时治疗对门诊患者来说具有优势且方便。

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