迪特拉棒联合紫外线B。斑块状银屑病的一种替代治疗方案。

Ditrastick combined with UVB. An alternative regimen for plaque psoriasis.

作者信息

Brandt H

机构信息

Department of Dermatology, Helsinki University Central Hospital, Finland.

出版信息

Acta Derm Venereol Suppl (Stockh). 1989;146:102-3.

PMID:2609849

Abstract

Two comparable groups of 15 out-patients with symmetrical plaque psoriasis were included in an open right-left comparison study. Paraffin based, 3% dithranol (anthralin) sticks (Ditrastick), Orion Pharmaceutica, Espoo, Finland) and 0.5-1% dithranol in white petrolatum were used in combination with UVB. Both suberythema doses and MED doses were used and the effect of UVB-pretreatment was studied. Pretreatment with UVB and combination therapy with dithranol using suberythema doses of UVB seems to decrease dithranol irritation and shorten the treatment time. Preliminary results are given.

摘要

两组各15例对称斑块状银屑病门诊患者参与了一项开放的左右对照研究。使用了芬兰埃斯波奥里安制药公司生产的石蜡基3%地蒽酚（蒽林）棒（Ditrastick）以及白色凡士林基质中含0.5 - 1%地蒽酚的制剂，并与紫外线B（UVB）联合使用。采用了亚红斑量和最小红斑量，同时研究了UVB预处理的效果。UVB预处理以及使用亚红斑量UVB的地蒽酚联合疗法似乎可减少地蒽酚刺激并缩短治疗时间。给出了初步结果。