Sandstedt P, Nordell L E, Henriksson K G
Acta Neurol Scand. 1982 Jul;66(1):130-44. doi: 10.1111/j.1600-0404.1982.tb04511.x.
106 muscle biopsies from patients with neuromuscular diseases or symptoms were assessed by routine inspection and quantitative examination. Eighty-six specimens were classed as pathological on routine evaluation and 84 on quantitative examination. Eleven specimens that were pathological on routine evaluation were "missed' by quantitative examination. Nine judged normal on routine examination were pathological according to quantitative criteria. Relative measures including the coefficient of variance, the difference between type I and type II fibres, and the difference between fascicles proved valuable for distinguishing between normal and pathological specimens. Quantitative analysis is a valuable complementary method which improves the detection of pathological states in muscle.
对106例患有神经肌肉疾病或有相关症状的患者的肌肉活检样本进行了常规检查和定量检查。在常规评估中，86个样本被归类为病理性样本，在定量检查中有84个被归类为病理性样本。11个在常规评估中为病理性的样本在定量检查中被“漏检”。9个在常规检查中判定为正常的样本根据定量标准为病理性样本。包括变异系数、I型和II型纤维之间的差异以及束间差异在内的相对测量方法在区分正常和病理性样本方面很有价值。定量分析是一种有价值的辅助方法，可提高对肌肉病理状态的检测。
