Bagnall K M, Harris P F, Jones P R
Anat Rec. 1982 Jun;203(2):293-9. doi: 10.1002/ar.1092030211.
This paper describes an extensive study of the growth of ossification centers in limb long bones of the human fetus from 8 to 26 weeks of conceptual age. Longitudinal measurements were made of the femur, tibia, fibula, humerus, radius, and ulna. Comparisons were made between bones on the left and right sides of the body and between the sexes. Standards are presented for the growth of these centers. They compare well with previous studies, any differences being accounted for by different methods of aging and measurement. A complicated picture of growth of the two sides of the fetal body is presented. Growth of the humerus, tibia, and fibula appears to be dominant on the left side of the body while growth in the femur is dominant on the right. At present, no explanation is available, but it is possible that factors such as manual dominance may be related. Evidence also is presented which suggests that the female fetus is in advance of the male in terms of ossification but only ater 21 weeks gestation.
本文描述了一项针对孕龄8至26周人类胎儿四肢长骨骨化中心生长情况的广泛研究。对股骨、胫骨、腓骨、肱骨、桡骨和尺骨进行了纵向测量。对身体左右两侧的骨骼以及不同性别的骨骼进行了比较。给出了这些骨化中心生长的标准。它们与先前的研究结果吻合良好，任何差异都是由不同的年龄判定和测量方法导致的。呈现了胎儿身体两侧生长情况的复杂图景。肱骨、胫骨和腓骨的生长似乎在身体左侧占主导，而股骨的生长在右侧占主导。目前尚无解释，但诸如用手习惯等因素可能与之相关，这是有可能的。也有证据表明，女胎在骨化方面比男胎超前，但这仅在妊娠21周之后。
