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喉气管狭窄内镜治疗成败的预测因素

Predictive factors of success or failure in the endoscopic management of laryngeal and tracheal stenosis.

作者信息

Simpson G T, Strong M S, Healy G B, Shapshay S M, Vaughan C W

出版信息

Ann Otol Rhinol Laryngol. 1982 Jul-Aug;91(4 Pt 1):384-8. doi: 10.1177/000348948209100412.

Abstract

Stenosis of the larynx and/or trachea presents perplexing problems. No one technique has proved totally satisfactory in the management of all varieties of stenosis. Recent reports have described the successful use of the CO2 laser in the endoscopic management of stenosis of the larynx and trachea. Failures of this technique need emphasis to assure appropriate selection of therapeutic method. Retrospectively, 49 cases of laryngeal stenosis, 6 cases of tracheal stenosis and 5 cases of combined laryngeal and tracheal stenosis were studied (total 60 patients) following treatment at the Boston University Affiliated Hospitals. Follow-up ranged from 1 to 8 years. Multiple procedures were required in 35 laryngeal patients. Of the laryngeal patients 39 were successfully managed (average number of procedures in successful cases 2.18). Of 11 tracheal patients with combined laryngeal and tracheal procedures, 3 were successfully managed (average number of procedures in successful cases 6). Failures in laryngeal stenosis included four patients in whom an adequate airway was not established though voice was present while maintaining tracheostomies. Thirteen patients failing endoscopic management required open surgery with good result. Factors associated with poor result or failure include circumferential scarring with cicatricial contracture, scarring wider than 1 cm in vertical dimension, tracheomalacia and loss of cartilage, previous history of severe bacterial infection associated with tracheostomy, and posterior laryngeal inlet scarring with arytenoid fixation. In these circumstances, multiple procedures, more extensive alternative open surgical techniques, or maintenance of tracheostomy were necessary. In successful cases only three or fewer procedures on average were required. The factors associated with failure or success of endoscopic methods in the management of laryngotracheal stenosis, including use of the CO2 laser and soft Silastic stents, are analyzed.

摘要

喉和/或气管狭窄带来了令人困惑的问题。在处理所有类型的狭窄时,没有一种技术被证明是完全令人满意的。最近的报告描述了二氧化碳激光在内镜下处理喉和气管狭窄方面的成功应用。需要强调该技术的失败情况,以确保正确选择治疗方法。我们回顾性研究了波士顿大学附属医院治疗的49例喉狭窄、6例气管狭窄和5例喉气管联合狭窄患者(共60例)。随访时间为1至8年。35例喉狭窄患者需要进行多次手术。在这些喉狭窄患者中,39例得到成功治疗(成功病例的平均手术次数为2.18次)。在11例接受喉气管联合手术的气管狭窄患者中,3例得到成功治疗(成功病例的平均手术次数为6次)。喉狭窄的失败病例包括4例患者,尽管他们在维持气管造口的情况下有声音,但未能建立足够的气道。13例内镜治疗失败的患者需要进行开放性手术,效果良好。与治疗效果不佳或失败相关的因素包括伴有瘢痕挛缩的环形瘢痕、垂直径大于1 cm的瘢痕、气管软化和软骨缺失、既往与气管造口相关的严重细菌感染史以及伴有杓状软骨固定的喉后入口瘢痕。在这些情况下,需要进行多次手术、更广泛的替代性开放性手术技术或维持气管造口。在成功的病例中,平均只需要进行三次或更少的手术。我们分析了在内镜治疗喉气管狭窄中与失败或成功相关的因素,包括二氧化碳激光和软质硅橡胶支架的使用情况。

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