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先天性与后天性声门下狭窄儿童行环状气管狭窄切除术(CTSR)的疗效

Efficacy of Cricotracheal Stenosis Resection (CTSR) Among Children with Congenital vs. Acquired Sub-glottic Stenosis.

作者信息

Alshammari Jaber, Halawani Mohammed, Arafat Abdullah, Alkhaldi Abdullah, Masud Nazish

机构信息

Division of Otolaryngology Head & Neck Surgery, King Abdulaziz Medical City (KAMC), King Abdullah Specialized Children Hospital (KASCH), National Guard Health Affairs (NGHA), Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center Riyadh (KAIMRC), Riyadh, Saudi Arabia.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):1755-1761. doi: 10.1007/s12070-023-03731-3. Epub 2023 Apr 3.

Abstract

Sub-glottic Stenosis (SGS) treatment in children is challenging because there is no standard algorithm to follow; however, the use of endoscopic techniques in SGS treatment has emerged over the last decades and has advanced. The aim of this study was to assess the efficacy of Cricotracheal Stenosis Resection (CTSR) among children with congenital vs. acquired SGS. In this retrospective study, we reviewed the charts of 22 patients who underwent endoscopic intervention as the primary modality of treatment for SGS at King Abdulaziz Medical City from January 1, 2011 to October 31, 2019. Successful treatment was defined as: resolution of symptoms, restoration of a normal patent airway with no stenosis, and decannulation. Out of 22 patients, 14 cases were acquired and 8 were congenital SGS. Most of the patients had grade 3 stenosis before surgery 15 (68%), followed by grade 1 stenosis among 4 (18.2%) and grade 2 stenosis was present in 3 (13.6%) patients. Postoperatively, 17 (77.3%) patients improved to grade zero, whereas grade 3 stenosis was not reported in any patient. The Mc-Nemar's test showed significant improvement between pre- and post-operative stenosis grade with test value = 22, and value = 0.003. This technique was successful among 18 (82%) patients with value ≤ 0.01. Irrespective of the differences in the age of patients, length, and character of stenosis among congenital and acquired groups, the endoscopic CTSR technique proved to be successful in both groups. We achieved a success rate of 86% in the acquired series, and 75% in the congenital series, which is a very promising result.

摘要

小儿声门下狭窄(SGS)的治疗具有挑战性,因为没有标准的治疗方案可供遵循;然而,在过去几十年中,内镜技术在SGS治疗中的应用逐渐兴起并取得了进展。本研究的目的是评估先天性与后天性SGS患儿行环状气管狭窄切除术(CTSR)的疗效。在这项回顾性研究中,我们查阅了2011年1月1日至2019年10月31日在阿卜杜勒阿齐兹国王医疗城接受内镜干预作为SGS主要治疗方式的22例患者的病历。成功治疗的定义为:症状缓解、恢复正常通畅气道且无狭窄、拔管。22例患者中,14例为后天性SGS,8例为先天性SGS。大多数患者术前为3级狭窄,共15例(68%),其次是4例(18.2%)为1级狭窄,3例(13.6%)为2级狭窄。术后,17例(77.3%)患者改善至0级,且无任何患者出现3级狭窄。Mc-Nemar检验显示术前和术后狭窄分级有显著改善,检验值 = 22,P值 = 0.003。该技术在18例(82%)P值≤0.01的患者中取得成功。无论先天性和后天性组患者年龄、狭窄长度和特征存在差异,内镜CTSR技术在两组中均被证明是成功的。我们在后天性组中的成功率为86%,先天性组为75%,这是一个非常有前景的结果。

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