Tsur H, Lipsker E
Ann Plast Surg. 1982 May;8(5):420-2. doi: 10.1097/00000637-198205000-00011.
A case of epithelioid sarcoma in a young man is described. At 16 years of age the patient had two skin ulcers removed from his hand, which were diagnosed as synovial sarcoma. At 21 years he underwent wide excision of the same area, including part of the thenar muscle, and a diagnosis was made of palmar fibromatosis with no confirmation of malignancy. Histological examination of biopsied growths three years later at age 24 showed the typical picture of epithelioid sarcoma. Following further excisions of local recurrences and removal of half the distal part of the forearm, the patient agreed to below-elbow amputation at age 27. He died within the year. The case presents the typical features of epithelioid sarcoma: apparently benign presentation on the hand in a yound man, a histological picture resembling other diseases resulting in misdiagnosis early in the disease, and local recurrences and metastasis. The misleading clinical and histological pictures of this insidious disease are discussed.
本文描述了一例年轻男性上皮样肉瘤病例。患者16岁时手部有两处皮肤溃疡被切除，诊断为滑膜肉瘤。21岁时，他接受了同一区域的广泛切除，包括部分大鱼际肌，诊断为掌部纤维瘤病，未确诊为恶性肿瘤。三年后的24岁时，对活检肿物进行组织学检查显示为典型的上皮样肉瘤表现。在进一步切除局部复发灶并切除前臂远端一半后，患者于27岁时同意行肘下截肢术。他在一年内死亡。该病例呈现出上皮样肉瘤的典型特征：年轻男性手部看似良性的表现、组织学表现类似于其他疾病导致疾病早期误诊、局部复发和转移。本文讨论了这种隐匿性疾病具有误导性的临床和组织学表现。
