成年雄性大鼠的氧气暴露与肺外呼吸道纤毛发生
Oxygen exposure and extrapulmonary respiratory tract ciliogenesis in adult male rats.
作者信息
Heino M, Laitinen L A
出版信息
Aviat Space Environ Med. 1982 Jun;53(6):580-2.
PMID:7115243
Abstract
Adult male rats were exposed to pure oxygen at atmospheric pressure for 12 and 24 h. Electron microscopic examination indicated ciliogenesis at every respiratory tract level. For the first time this investigation has established an oxygen insult which affects the epithelium of the entire extra-pulmonary respiratory tract, viz. ciliogenesis. An alteration in muco-ciliary clearance is suggested
摘要
成年雄性大鼠在常压下暴露于纯氧环境中12小时和24小时。电子显微镜检查显示在呼吸道各水平均有纤毛生成。本研究首次确立了一种影响整个肺外呼吸道上皮的氧损伤，即纤毛生成。提示黏液纤毛清除功能发生了改变。
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