Katsube Y, Mukai K, Silverberg S G
Cancer. 1982 Oct 15;50(8):1615-22. doi: 10.1002/1097-0142(19821015)50:8<1615::aid-cncr2820500826>3.0.co;2-k.
Five cases of the recently characterized cystic mesothelioma of the peritoneum are presented. The patients, all women, ranged in age from 23-50, and were seen with large, solitary or multiple, multicystic masses involving the abdominal and pelvic peritoneum. Histologically, they consisted of interconnecting cystic cavities lined by a single layer of flattened to cuboidal cells with variable nuclear atypia. These cells in one case showed ultrastructural features consistent with mesothelial origin. In follow-up periods ranging from 1-13 years, two patients have had recurrence of disease, but all patients are still alive. When these cases are combined with the ten previously reported, the recurrence rate in patients followed for two years or more is 50% (four of eight). This lesion may represent a clinically "borderline" variant between the better known benign (adenomatoid tumor) and malignant mesotheliomas of the peritoneum.
本文报告了5例最近才得以明确特征的腹膜囊性间皮瘤。患者均为女性，年龄在23岁至50岁之间，表现为累及腹盆腔腹膜的单个或多个多囊性大肿块。组织学上，它们由相互连通的囊腔组成，囊腔衬以单层扁平至立方形细胞，核异型性各异。其中1例的这些细胞显示出与间皮起源一致的超微结构特征。在1至13年的随访期内，有2例患者疾病复发，但所有患者均存活。当将这些病例与之前报告的10例相结合时，随访两年或更长时间的患者复发率为50%（8例中的4例）。这种病变可能代表了腹膜中较知名的良性（腺瘤样瘤）和恶性间皮瘤之间临床上的“交界性”变体。
