Kalpoyiannis N, Androulakis N, Hadjigerorgiou E, Papadatos J, Oeconomidou O, Nicolopoulos D
Clin Pediatr (Phila). 1982 Oct;21(10):602-6. doi: 10.1177/000992288202101008.
In a review of treatment of neonatal jaundice, the authors studied the impact of phototherapy on outcome. From comparing exchange transfusion treatment over a 39-month period prior to the availability of phototherapy to a 39-month period incorporating phototherapy in the treatment regimen, the authors conclude that phototherapy (1) acts slowly but constantly to reduce bilirubin levels and (2) is effective even in severe hemolytic jaundice, but its effectiveness is inversely related to the degree of hemolysis. While phototherapy can never totally replace exchange transfusion, it can certainly reduce the number of transfusions needed.
在一篇关于新生儿黄疸治疗的综述中，作者研究了光疗对治疗结果的影响。通过比较在光疗可用之前的39个月期间的换血疗法与在治疗方案中纳入光疗的39个月期间的情况，作者得出结论：光疗（1）降低胆红素水平的作用缓慢但持续，（2）即使在严重溶血性黄疸中也有效，但其有效性与溶血程度呈负相关。虽然光疗永远无法完全取代换血疗法，但它肯定可以减少所需的输血次数。
