Baarsma R, Feijen J, Houthoff J
J Bioeng. 1978 Jun;2(3-4):251-7.
Different materials were compared as implants in performing a myringoplasty on rats immediately after making a total perforation, (autologous fascia, homologous tympanic membrane, homologous collagen, heterologous collagen, heterologous amnion and proplast). As a reference one group of rats had no myringoplasty done after perforating their drums. The animals were examined regularly, then killed after 40 and 64 weeks. Macroscopically and microscopically proplast and homologous collagen were very inferior to homograft tympanic membrane and autologous fascia. The best results were obtained both macroscopically and histologically with heterologous collagen and heterologous amnion.
在大鼠鼓膜完全穿孔后立即进行鼓膜成形术时，对不同材料作为植入物进行了比较（自体筋膜、同种异体鼓膜、同种异体胶原蛋白、异种胶原蛋白、异种羊膜和普罗普拉斯）。作为对照，一组大鼠在鼓膜穿孔后未进行鼓膜成形术。定期对动物进行检查，然后在40周和64周后处死。宏观和微观检查显示，普罗普拉斯和同种异体胶原蛋白远不如同种异体移植鼓膜和自体筋膜。异种胶原蛋白和异种羊膜在宏观和组织学上均取得了最佳效果。
