Eddy C A, Bajpai V K
Fertil Steril. 1982 Sep;38(3):354-63. doi: 10.1016/s0015-0282(16)46519-2.
The postoperative time course of healing following tubal microsurgery was examined in the rabbit by transmission electron microscopy (TEM) and scanning electron microscopy (SEM) and was correlated with changes in fertility. Groups of animals were bred or used for morphologic studies on days 1, 2, 3, 4, 7, and 14 after surgery. During the first 4 postoperative days, a major loss of ciliary and secretory activity occurred and was characterized by disruption of subcellular organelles. Tissue damage was restricted to within several millimeters of the anastomosis. Healing was well advanced by day 7 and was largely complete by day 14. Corresponding changes in fertility were observed. A significant decline in fertility was noted on the first postoperative day. Thereafter, fertility progressively improved and was normal by day 14.
通过透射电子显微镜(TEM)和扫描电子显微镜(SEM)对家兔输卵管显微手术后的愈合时间进程进行了检查,并将其与生育力变化相关联。在手术后第1、2、3、4、7和14天,将动物分组进行繁殖或用于形态学研究。术后前4天,纤毛和分泌活动出现重大损失,其特征为亚细胞器破坏。组织损伤局限于吻合口几毫米范围内。到第7天时愈合进展良好,到第14天时基本完成。观察到生育力有相应变化。术后第一天生育力显著下降。此后,生育力逐渐改善,到第14天时恢复正常。