Edmonds D K, Lindsay K S, Miller J F, Williamson E, Wood P J
Fertil Steril. 1982 Oct;38(4):447-53.
Measurements of human chorionic gonadotropin (hCG) have been used to assess early embryo loss in women. Urine samples obtained from a control group of sterilized women with normal ovulatory menstrual cycles enabled a concentration limit of 56 IU/l to be determined so that any nontrophoblastic hCG or other cross-reacting compounds could be accounted for. One hundred ninety-eight ovulatory cycles were collected from a normal population attempting to conceive. Fecundability was 22% to 27% for this population. The risk of pregnancy in exposed ovulatory cycles was 59.6%; however, 61.9% of conceptuses will be lost prior to 12 weeks. Most of these losses (91.7%) occur subclinically, without the knowledge of the mother.
人绒毛膜促性腺激素（hCG）的测量已被用于评估女性早期胚胎丢失情况。从排卵月经周期正常的绝育女性对照组获取的尿液样本，确定了浓度限值为56 IU/l，以便能够解释任何非滋养层hCG或其他交叉反应化合物。从试图受孕的正常人群中收集了198个排卵周期。该人群的受孕几率为22%至27%。暴露的排卵周期中怀孕的风险为59.6%；然而，61.9%的胚胎将在12周前丢失。这些丢失大多（91.7%）发生在亚临床阶段，母亲并不知晓。
