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氨基糖苷类抗生素对奶牛的低钙血症作用。

Hypocalcemic effect of aminoglycoside antibiotics in the dairy cow.

作者信息

Crawford L M, Campbell D L, Harvey T

出版信息

Can J Comp Med. 1977 Jul;41(3):251-6.

Abstract

The effect of the parenteral administration of aminoglycoside antibiotics on the blood calcium concentration in dairy cows was investigated. Gentamicin was tested in vitro in blood drawn from cows, dihydrostreptomycin was tested in nonlactating cows and neomycin was tested in postpartum cows. The total and bound calcium fractions were significantly reduced by all three antibiotics. No change occurred in the unbound calcium fractions. Caution is advised in the use of these drugs in postpartum cows, especially those with a history of milk fever.

摘要

研究了胃肠外给予氨基糖苷类抗生素对奶牛血钙浓度的影响。对从奶牛采集的血液进行庆大霉素体外试验,对非泌乳奶牛进行双氢链霉素试验,对产后奶牛进行新霉素试验。所有三种抗生素均使总钙和结合钙部分显著降低。未结合钙部分未发生变化。建议在产后奶牛,尤其是有产乳热病史的奶牛中谨慎使用这些药物。

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本文引用的文献

1
Neomycin-curare neuromuscular block and reversal in cats.
Anesthesiology. 1969 Sep;31(3):228-32. doi: 10.1097/00000542-196909000-00006.
3
Hypocalcemia without paresis in cows.奶牛无轻瘫的低钙血症
J Am Vet Med Assoc. 1966 Aug 15;149(4):402-5.
4
Correlation of bovine serum macroglobulin and calcium at parturition.
J Dairy Sci. 1974 Jan;57(1):41-8. doi: 10.3168/jds.S0022-0302(74)84829-0.
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25-Hydroxycholecalciferol (25-OHD3). I. Treatment for parturient paresis.
J Dairy Sci. 1973 Jul;56(7):885-8. doi: 10.3168/jds.S0022-0302(73)85272-5.
7
Combating milk fever.
J Dairy Sci. 1974 Aug;57(8):933-44. doi: 10.3168/jds.S0022-0302(74)84989-1.
9
The cumulative neuromuscular blocking effect of neomycin.
Arch Int Pharmacodyn Ther. 1974 Aug;210(2):288-97.
10
Antibiotic blockade of neuromuscular function.抗生素对神经肌肉功能的阻断作用。
Annu Rev Pharmacol. 1972;12:169-84. doi: 10.1146/annurev.pa.12.040172.001125.

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