Lindblad L E, Wallin B G, Bevegård S
J Auton Nerv Syst. 1982 May;5(3):373-9. doi: 10.1016/0165-1838(82)90078-9.
Carotid baroreceptor modulation of forearm vascular resistance was examined in 6 healthy subjects, each subject participating in 6 identical experimental runs. Forearm vascular resistance was calculated from simultaneous measurements of blood pressure and forearm blood flow (venous occlusion plethysmography). Carotid baroreceptor activity was modified by neck suction technique. To compare the effects of dynamic and static changes of baroreceptor activity neck suction was increased as a ramp lasting 6 s from -10 mm Hg (control) to -40 mm Hg and then maintained at this level. Measurements were started 15 s before and 9 s ('early') and 30 s ('late') after the onset of the suction ramp. Vascular resistance showed a significant (P less than 0.01) decrease during 'early' suction; but recovered partially and during 'late' suction there was no significant difference from control. The results indicate that carotid baroreceptors do modulate vascular resistance in the forearm and that the effect is more pronounced in response to dynamic than to static changes in baroreceptor input.
在6名健康受试者中研究了颈动脉压力感受器对前臂血管阻力的调节作用，每名受试者参与6次相同的实验。通过同时测量血压和前臂血流量（静脉阻塞体积描记法）来计算前臂血管阻力。采用颈部吸引技术改变颈动脉压力感受器的活动。为了比较压力感受器活动的动态和静态变化的影响，颈部吸引以斜坡形式从-10 mmHg（对照）增加到-40 mmHg，持续6秒，然后维持在该水平。在吸引斜坡开始前15秒、开始后9秒（“早期”）和30秒（“晚期”）开始测量。在“早期”吸引期间，血管阻力显著（P<0.01）降低；但部分恢复，在“晚期”吸引期间与对照无显著差异。结果表明，颈动脉压力感受器确实调节前臂血管阻力，并且对压力感受器输入的动态变化的反应比对静态变化的反应更明显。
