Zylberberg B, Salat-Baroux J, Ravina J H, Demarcourt V, Dormont D
J Gynecol Obstet Biol Reprod (Paris). 1982;11(3):365-70.
While it is useful to carry out aspiration from the Pouch of Douglas for screening for cancer of the ovary, the technique is irreplaceable for the follow-up of tumours that have been operated on or irradiated or treated with chemotherapy. We have carried out 1,353 aspirations: 189 of these which were done routinely have been equivocal. 380 aspirations that were carried out because of abnormal symptoms led to the discovery of 26 cancers of which 2 were very early ones. 784 aspirations were carried out for follow-up. There were in all 4.8% blank aspirations, 0.5% false positives and 1.6% false negatives, which is an indication of the reliability of the method so long as certain points in the technique are carefully followed. These figures, which are quoted as a percentage of the total number of aspirations, however, become more important when considered as a percentage of the number of cancers that were diagnosed (5.5% false positive and 18% false negatives). Furthermore, the level of C.E.A. in peritoneal fluid is a method which can be added to cytology in following up the progress of the disease which is not to be dismissed.
虽然对Douglas窝进行穿刺抽吸以筛查卵巢癌很有用，但该技术对于已接受手术、放疗或化疗的肿瘤的随访来说是不可替代的。我们已进行了1353次穿刺抽吸：其中189次常规穿刺抽吸结果不明确。因异常症状进行的380次穿刺抽吸发现了26例癌症，其中2例为极早期癌症。784次穿刺抽吸用于随访。总共有4.8%的穿刺抽吸结果为空，0.5%为假阳性，1.6%为假阴性，这表明只要严格遵循该技术的某些要点，该方法是可靠的。然而，这些数字作为穿刺抽吸总数的百分比时，若作为已确诊癌症数量的百分比来看就更重要了（5.5%假阳性和18%假阴性）。此外，在疾病进展的随访中，腹水中癌胚抗原（CEA）水平是一种可补充细胞学检查的方法，不容忽视。
