Rattner B A, Sileo L, Scanes C G
J Reprod Fertil. 1982 Sep;66(1):147-55. doi: 10.1530/jrf.0.0660147.
Bobwhite quail were fed concentrations of parathion (0,50, 100, 200 or 400 p.p.m.) for 10 days. Food intake, body weight change, brain acetylcholinesterase activity, egg production, and ovary weight were reduced in a dose-dependent manner. In a second experiment, birds were fed 0, 25 or 100 p.p.m. parathion or pair-fed control food to equate consumption in the 100 p.p.m. group. Egg production was not affected in birds fed 25 p.p.m. or in the pair-fed group, but the daily time of oviposition was more variable than in the control group. Cessation of egg production, inhibition of follicular development, and reduced plasma LH concentration were observed in birds fed 100 p.p.m. parathion. These findings indicate that exposure to parathion can impair reproduction, possibly by altering gonadotrophin secretion.
给雄性白喉鹑喂食浓度为0、50、100、200或400 ppm的对硫磷，持续10天。食物摄入量、体重变化、脑乙酰胆碱酯酶活性、产蛋量和卵巢重量均呈剂量依赖性降低。在第二项实验中，给鸟类喂食0、25或100 ppm的对硫磷，或成对喂食对照食物，以使100 ppm组的摄入量相等。喂食25 ppm对硫磷的鸟类或成对喂食组的产蛋量未受影响，但每天的产卵时间比对照组更具变化性。在喂食100 ppm对硫磷的鸟类中观察到产蛋停止、卵泡发育受到抑制以及血浆促黄体生成素浓度降低。这些发现表明，接触对硫磷可能会通过改变促性腺激素分泌而损害繁殖能力。
