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丙酸倍氯米松气雾剂用于儿童哮喘的三至五年随访

A three- to five-year follow-up of the use of the aerosol steroid, beclomethasone dipropionate, in childhood asthma.

作者信息

Godfrey S, Balfour-Lynn L, Tooley M

出版信息

J Allergy Clin Immunol. 1978 Dec;62(6):335-9. doi: 10.1016/0091-6749(78)90133-1.

Abstract

Nineteen asthmatic children treated with the aerosol steroid, beclomethasone dipropionate, were followed 3 to 5 yr. Good control was maintained in all but one child throughout, although 73% have needed 1 or 2 wk of supplementary oral steroids per year for exacerbations. Growth has been along the percentile on which the child entered the study. No serious side effects have been encountered among 41 children treated between 1 and 5 yr with beclomethasone dipropionate. Seventeen percent needed prolonged alternate-day oral steroids, although all but one child did eventually return to good control with beclomethasone dipropionate.

摘要

对19名接受气雾剂类固醇二丙酸倍氯米松治疗的哮喘儿童进行了3至5年的随访。除一名儿童外,所有儿童在整个随访期间病情都得到了良好控制,不过73%的儿童每年因病情加重需要1至2周的补充口服类固醇治疗。生长情况一直处于儿童进入研究时的百分位水平。在1至5岁接受二丙酸倍氯米松治疗的41名儿童中,未出现严重副作用。17%的儿童需要长期隔日口服类固醇治疗,不过除一名儿童外,所有儿童最终都通过二丙酸倍氯米松恢复了良好控制。

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