Guikovaty J P, André G, Nisand I, Grob J C, Méthlin G, Dellenbach P
J Gynecol Obstet Biol Reprod (Paris). 1978 May-Jun;7(4):809-17.
The authors have developed a method of measuring placental blood flow using intravenous injection of Xenon 133, the method being derived from that described by Rekonen. The technique is reliable and without any danger. The measurements were taken in the last 4 weeks of 25 normal pregnancies and 12 where intra-uterine growth was retarded. The placental blood flow is 92.02 +/- 16.34 ml s100 ml per minute in normal pregnancies at the end of which infants with a weight above or equal to the 10th percentile were born (the mean percentile was 46.69 +/- 25.36). The placental blood flow was 52.29 +/- 17.31 ml/100 ml per minute in cases with retarded intra-uterine growth where the infants were lighter than the 10th percentile (mean percentile 5.08 +/- 1.83). The difference between the two groups is highly significant (p less than 0.001).
作者们研发出一种通过静脉注射氙133来测量胎盘血流的方法，该方法源自雷科宁所描述的方法。这项技术可靠且没有任何危险。对25例正常妊娠和12例宫内生长受限的孕妇在妊娠最后4周进行了测量。在正常妊娠中，胎盘血流为每分钟92.02±16.34毫升/100毫升，妊娠结束时出生的婴儿体重高于或等于第10百分位数（平均百分位数为46.69±25.36）。在宫内生长受限且婴儿体重低于第10百分位数的病例中，胎盘血流为每分钟52.29±17.31毫升/100毫升（平均百分位数5.08±1.83）。两组之间的差异非常显著（p小于0.001）。
