Novikova N A, Solomatina E S, Kapel'ko V I
Kardiologiia. 1982;22(6):78-82.
Experiments on the isolated hearts of guinea pigs have shown that administration of dinitrophenol in the concentrations of 0.01-0.10 mmol elicited, depending on the dose given, a decrease in pressure of a latex balloon, placed into the cavity of the left ventricle and an increase in the displacement of the SI segment on the ECG, recorded from the subendocardial layer of the apex. It is established that the rate of the coronary flow, limiting washing out of K+ and other metabolites determines the degree of depression of the contractile function with energy formation disorders and also its restoration during reoxygenation.
对豚鼠离体心脏进行的实验表明，给予浓度为0.01 - 0.10 mmol的二硝基苯酚时，根据给药剂量不同，置于左心室腔的乳胶气球压力会降低，从心尖内膜下层记录的心电图上的SI段位移会增加。已确定，冠状动脉血流速率限制了钾离子和其他代谢产物的清除，它决定了能量生成紊乱时收缩功能的抑制程度以及复氧过程中收缩功能的恢复程度。
