Kapel'ko V I, Novikova N A, Saks V A
Fiziol Zh SSSR Im I M Sechenova. 1988 Feb;74(2):202-8.
Changes in the cardiac pump function, contractility, relaxation and distensibility in progressive metabolic blockade induced with dinitrophenol, were compared in the guinea pig isolated heart. A fall in relaxation and distensibility occurred first and was more obvious than a fall in contractility or the cardiac output. The same relationships were observed in isolated hearts of rats with myocardial phosphocreatine deficiency. The fall in relaxation and distensibility seem to be the necessary sign of acute or chronic myocardial energy deficiency.
在豚鼠离体心脏中，比较了用二硝基苯酚诱导的进行性代谢阻滞过程中心脏泵功能、收缩性、舒张性和扩张性的变化。舒张性和扩张性首先下降，且比收缩性或心输出量的下降更明显。在心肌磷酸肌酸缺乏的大鼠离体心脏中也观察到了相同的关系。舒张性和扩张性的下降似乎是急性或慢性心肌能量缺乏的必要标志。
