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基于运动功能减退大鼠心震图数据的心肌收缩功能评估

[Evaluation of myocardial contractile function based on seismocardiographic data of rats in hypokinesia].

作者信息

Kuznetsov V I

出版信息

Kosm Biol Aviakosm Med. 1982 Jul-Aug;16(4):35-8.

PMID:7120906
Abstract

The possibility of seismocardiographic recording in rats has been explored and SCG time and amplitude parameters have been determined. The measurements have been performed in normal rats and hypokinetic rats with an altered cardiac contractility. The SCG data obtained in hypokinetic rats have been compared with the results derived from contractility studies by heart catheterization and subsequent calculation of contraction strength and velocity. It has been shown that the data compared are similar on hypokinetic days 1 and 5. This suggests that the seismocardiographic method of studying heart contractility function of rats is adequate for integral evaluations of the strength and velocity of cardiac contractions in chronic experiments. On hypokinetic days 15 and 30 the data obtained by catheterization and seismocardiographically are at variance. This may be attributed to muscle mass losses and variations in the rigidity of "internal" bonding.

摘要

已经探索了在大鼠中进行心震图记录的可能性,并确定了心震图的时间和幅度参数。这些测量是在正常大鼠和心脏收缩力改变的运动功能减退大鼠中进行的。将运动功能减退大鼠获得的心震图数据与通过心导管插入术进行收缩力研究并随后计算收缩强度和速度得出的结果进行了比较。结果表明,在运动功能减退的第1天和第5天,所比较的数据相似。这表明,研究大鼠心脏收缩功能的心震图方法足以对慢性实验中心脏收缩的强度和速度进行整体评估。在运动功能减退的第15天和第30天,通过导管插入术和心震图获得的数据存在差异。这可能归因于肌肉质量损失和“内部”结合刚度的变化。

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