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The remarkable substrate activity for phenylethanolamine N-methyltransferase of some conformationally defined phenylethylamines lacking a side-chain hydroxyl group. Conformationally defined adrenergic agents. 6.

作者信息

Rafferty M F, Grunewald G L

出版信息

Mol Pharmacol. 1982 Jul;22(1):127-32.

PMID:7121446
Abstract
摘要

相似文献

1
The remarkable substrate activity for phenylethanolamine N-methyltransferase of some conformationally defined phenylethylamines lacking a side-chain hydroxyl group. Conformationally defined adrenergic agents. 6.
Mol Pharmacol. 1982 Jul;22(1):127-32.
2
Importance of the aromatic ring in adrenergic amines. Nonaromatic analoques of phenylethanolamine as substrates for phenylethanolamine N-methyltransferase.芳香环在肾上腺素能胺中的重要性。苯乙醇胺的非芳香类似物作为苯乙醇胺N-甲基转移酶的底物。
Mol Pharmacol. 1975 Sep;11(5):694-9.
3
Conformational and steric aspects of phenylethanolamine and phenylethylamine analogues as substrates or inhibitors of phenylethanolamine N-methyltransferase.苯乙醇胺和苯乙胺类似物作为苯乙醇胺N-甲基转移酶底物或抑制剂的构象和空间方面
Mol Pharmacol. 1989 Jan;35(1):93-7.
4
The effect of beta-adrenergic blocking agents on the rat adrenal phenylethanolamine-N-methyltransferase activity.β-肾上腺素能阻断剂对大鼠肾上腺苯乙醇胺-N-甲基转移酶活性的影响。
Pol J Pharmacol Pharm. 1973 May-Jun;25(3):237-41.
5
Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase.苯乙醇胺N-甲基转移酶活性底物的构象要求
J Med Chem. 1988 Jan;31(1):169-71. doi: 10.1021/jm00396a026.
6
Conformational preferences of amphetamine analogues for inhibition of phenylethanolamine N-methyltransferase. Conformationally defined adrenergic agents. 5.苯丙胺类似物对苯乙醇胺N-甲基转移酶抑制作用的构象偏好。构象明确的肾上腺素能药物。5。
Mol Pharmacol. 1981 Sep;20(2):377-81.
7
Position of a chloro substituent on phenylethanolamine as a determinant of methylation by rabbit adrenal norepinephrine N-methyltransferase.苯乙醇胺上氯取代基的位置作为兔肾上腺去甲肾上腺素N-甲基转移酶甲基化作用的一个决定因素。
Res Commun Chem Pathol Pharmacol. 1977 Nov;18(3):577-80.
8
Conformational preferences of dopamine analogues for inhibition of norepinephrine N-methyltransferase. Conformationally defined adrenergic agents.
Life Sci. 1982 Sep 6;31(10):993-1000. doi: 10.1016/0024-3205(82)90171-0.
9
Stereochemical aspects of phenylethanolamine analogues as substrates of phenylethanolamine N-methyltransferase.苯乙醇胺类似物作为苯乙醇胺N-甲基转移酶底物的立体化学方面
J Med Chem. 1988 Oct;31(10):1984-6. doi: 10.1021/jm00118a021.
10
Heterogeneity of N-and O-methyltransferases.N-甲基转移酶和O-甲基转移酶的异质性
Mol Pharmacol. 1970 Jan;6(1):78-84.

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1
Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity.肾上腺素合成酶PNMT对生理底物去甲肾上腺素的分子识别及其甲基转移酶活性的影响因素。
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