Nirankari V S, Katzen L E, Richards R D, Karesh J W, Lakhanpal V, Billings E
Ophthalmology. 1982 Jun;89(6):677-83. doi: 10.1016/s0161-6420(82)34739-9.
A prospective clinical study of radial keratotomy was conducted at the University of Maryland. Results of surgery on 33 eyes of 19 patients with a minimum follow-up of seven months and a mean of 13.8 months are reported. There were eight patients (15 eyes) who needed adequate unaided visual acuity for occupational purposes. Preoperative visual acuity was 20/400 in 79% of eyes. Postoperative visual acuity was 20/50 or better in 48% of cases. However, in patients with preoperative refractive errors of 5 diopters or less, postoperative visual acuity was 20/50 or better in 84% of cases. Average decrease in myopia was 2.5 diopters. Decrease in myopia following radial keratotomy did not correlate with corneal curvature or whether 8 or 16 incision technique was used. However, there was a very significant (P = 0.001) difference in postoperative visual acuity of patients with refractive error of 5 diopters or less, as compared to those with greater than 5 diopters of myopia. Complications included corneal scarring, vascularization, and glare. No microperforation or endothelial cell loss was observed.
马里兰大学开展了一项关于放射状角膜切开术的前瞻性临床研究。报告了19例患者33只眼睛的手术结果，这些患者的最短随访期为7个月，平均随访期为13.8个月。有8名患者（15只眼睛）因职业目的需要具备足够的裸眼视力。79%的眼睛术前视力为20/400。48%的病例术后视力达到20/50或更好。然而，术前屈光不正为5屈光度或更低的患者中，84%的病例术后视力达到20/50或更好。近视平均降低2.5屈光度。放射状角膜切开术后近视的降低与角膜曲率或采用8切口还是16切口技术无关。然而，与近视度数大于5屈光度的患者相比，屈光不正为5屈光度或更低的患者术后视力存在非常显著的差异（P = 0.001）。并发症包括角膜瘢痕形成、血管化和眩光。未观察到微小穿孔或内皮细胞丢失。
