Gambert S R, Csuka M E, Duthie E H, Tiegs R
Postgrad Med. 1982 Sep;72(3):147-52. doi: 10.1080/00325481.1982.11716189.
An understanding of the normal aging process and its effects on common laboratory values is essential when evaluating the elderly patient. Although results of research to determine precise changes in values for this age-group in hemoglobin, hematocrit, white cell count, ESR, serum bilirubin and alkaline phosphatase, SGOT, and glomerular filtration have not been conclusive in most instances, some of the findings described here warrant consideration. We believe that the established normal ranges for these values do not need to be significantly modified for the elderly and that slight deviations from them are normal for the healthy patient. However, all abnormal test results should not be attributed to aging alone; the clinician might overlook the need for further diagnostic workup for possible serious disorders.
在评估老年患者时,了解正常衰老过程及其对常见实验室检查值的影响至关重要。尽管在大多数情况下,关于该年龄组血红蛋白、血细胞比容、白细胞计数、红细胞沉降率、血清胆红素和碱性磷酸酶、谷草转氨酶以及肾小球滤过率等指标精确变化的研究结果尚无定论,但此处描述的一些发现值得考虑。我们认为,这些指标既定的正常范围无需针对老年人进行显著修改,对于健康的老年患者而言,与这些范围存在轻微偏差是正常现象。然而,所有异常的检查结果不应仅归因于衰老;临床医生可能会忽视对可能存在的严重疾病进行进一步诊断检查的必要性。