与西咪替丁和肝功能衰竭相关的可逆性粒细胞缺乏症。
Reversible agranulocytosis in association with cimetidine and hepatic failure.
作者信息
Lewis D S, Beck E R
出版信息
Postgrad Med J. 1982 Jul;58(681):443-4. doi: 10.1136/pgmj.58.681.443.
Abstract
A patient is described who developed agranulocytosis in the context of hepatic failure and cimetidine therapy. The close temporal relationship between discontinuation of the drug and granulopoietic recovery is considered to imply a role for cimetidine in the mechanism of the agranulocytosis.
摘要
本文描述了一名在肝衰竭和西咪替丁治疗背景下发生粒细胞缺乏症的患者。药物停用与粒细胞生成恢复之间紧密的时间关系被认为意味着西咪替丁在粒细胞缺乏症机制中起作用。
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Reversible agranulocytosis in association with cimetidine and hepatic failure.与西咪替丁和肝功能衰竭相关的可逆性粒细胞缺乏症。
Postgrad Med J. 1982 Jul;58(681):443-4. doi: 10.1136/pgmj.58.681.443.
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引用本文的文献
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Haematological adverse effects of histamine H2-receptor antagonists.组胺H2受体拮抗剂的血液学不良反应。
Med Toxicol Adverse Drug Exp. 1988 Nov-Dec;3(6):430-48. doi: 10.1007/BF03259895.
本文引用的文献
1
Cimetidine clearance and bioavailability in hepatic cirrhosis.西咪替丁在肝硬化中的清除率和生物利用度。
Clin Pharmacol Ther. 1981 Feb;29(2):191-7. doi: 10.1038/clpt.1981.30.
2
[Plasma concentrations of cimetidine in cirrhotic and non-cirrhotic patients with upper digestive tract hemorrhage (author's transl)].肝硬化和非肝硬化上消化道出血患者西咪替丁的血浆浓度（作者译）
Gastroenterol Clin Biol. 1981 Feb;5(2):155-60.
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Transient neutropenia in a patient receiving cimetidine.
Gastroenterology. 1977 Sep;73(3):635-8.
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Cimetidine and Agranulocytosis.
Ann Intern Med. 1978 Apr;88(4):579-80. doi: 10.7326/0003-4819-88-4-579_2.
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Cimetidine and granulocytopenia.西咪替丁与粒细胞减少症
Ann Intern Med. 1979 Feb;90(2):264-5. doi: 10.7326/0003-4819-90-2-264.
6
Pharmacological evaluation of cimetidine, a new histamine H2-receptor antagonist, in healthy man.新型组胺H2受体拮抗剂西咪替丁在健康人体中的药理学评价。
Br J Clin Pharmacol. 1975 Dec;2(6):481-6. doi: 10.1111/j.1365-2125.1975.tb00564.x.
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