小鼠行为异常的关键时期。
Critical periods for behavioral anomalies in mice.
作者信息
Rodier P M
出版信息
Environ Health Perspect. 1976 Dec;18:79-83. doi: 10.1289/ehp.761879.
Abstract
While mice have been used less frequently than rats in behavioral research, there use has some advantages in teratological studies. The development of the mouse CNS has been investigated more extensively than that of the rat. Since time of insult has been found to be an important factor in effects on both anatomy and behavior, data on the sequence of events in CNS development are valuable in planning and interpreting behavioral assessments of potential teratogens. A comparison of studies in mice and rats suggests that behavioral effects of teratogens are similar in the two species and demonstrates that mice can be used successfully in a variety of behavioral evaluations.
摘要
虽然在行为研究中，小鼠的使用频率低于大鼠，但在致畸学研究中，使用小鼠有一些优势。对小鼠中枢神经系统发育的研究比对大鼠的研究更为广泛。由于已发现损伤时间是影响解剖结构和行为的重要因素，因此中枢神经系统发育过程中事件序列的数据对于规划和解释潜在致畸剂的行为评估很有价值。对小鼠和大鼠研究的比较表明，致畸剂对这两个物种的行为影响相似，并表明小鼠可成功用于各种行为评估。
相似文献
1
Critical periods for behavioral anomalies in mice.
Environ Health Perspect. 1976 Dec;18:79-83. doi: 10.1289/ehp.761879.
2
Behavioral testing as a method for assessing risk.
Environ Health Perspect. 1976 Dec;18:75-8. doi: 10.1289/ehp.761875.
3
[Problems in transferring data from animals to man in behavioral teratology].
Cas Lek Cesk. 1982 Sep 17;121(37):1157-60.
4
Prenatal and early postnatal exposure to environmental toxicants.
Chic Med Sch Q. 1968 Winter;27(2):75-89.
5
A test battery for screening behavioral teratogens in mice.
Neurobehav Toxicol Teratol. 1985 Nov-Dec;7(6):727-31.
6
5-Methoxy-N,N-dimethyltryptamine: behavioral and toxicological effects in animals.
Biol Psychiatry. 1976 Jun;11(3):355-8.
7
Behavioral methods in reproductive and developmental toxicology.
Neurobehav Toxicol Teratol. 1985 Nov-Dec;7(6):745-52.
8
Behavioral consequences of interference with CNS development in the early fetal period.
Teratology. 1979 Jun;19(3):327-36. doi: 10.1002/tera.1420190308.
9
Inhibitory avoidance acquisition in adult rats exposed to a combination of ethanol and methylmercury during central nervous system development.
Behav Brain Res. 2010 Aug 25;211(2):191-7. doi: 10.1016/j.bbr.2010.03.032. Epub 2010 Mar 25.
10
Behavioral effects of repeated aluminum administration in the rat.
Tokai J Exp Clin Med. 1992 Dec;17(5-6):155-9.
引用本文的文献
1
Clinically relevant experimental rodent models of diabetic foot ulcer.
Mol Cell Biochem. 2022 Apr;477(4):1239-1247. doi: 10.1007/s11010-022-04372-w. Epub 2022 Jan 28.
2
PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene.
Toxicol Sci. 2012 Jan;125(1):233-47. doi: 10.1093/toxsci/kfr261. Epub 2011 Oct 10.
3
Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation.
Behav Brain Res. 2009 Dec 28;205(2):499-504. doi: 10.1016/j.bbr.2009.08.006. Epub 2009 Aug 12.
4
Developmental neurotoxicology of endocrine disruptors and pesticides: identification of information gaps and research needs.
Environ Health Perspect. 1998 Jun;106 Suppl 3(Suppl 3):807-11. doi: 10.1289/ehp.98106807.
5
DDT/DDE and infant exposure.
Environ Health Perspect. 1997 Jan;105(1):14-5. doi: 10.1289/ehp.105-1469827.
6
The concern for developmental neurotoxicology: is it justified and what is being done about it?
Environ Health Perspect. 1995 Sep;103 Suppl 6(Suppl 6):147-51. doi: 10.1289/ehp.95103s6147.
7
Gestational caffeine modifies offspring behaviour in mice.
Psychopharmacology (Berl). 1981;75(1):69-74. doi: 10.1007/BF00433505.
8
Research strategies for behavioral teratology studies.
Environ Health Perspect. 1976 Dec;18:85-94. doi: 10.1289/ehp.761885.
本文引用的文献
1
Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse.
Nature. 1961 Nov 25;192:766-8. doi: 10.1038/192766b0.
2
An autoradiographic analysis of histogenesis in the mouse cerebellum.
Exp Neurol. 1961 Oct;4:277-96. doi: 10.1016/0014-4886(61)90055-3.
3
The development of the mammalian nervous system. I. Malformations of the brain, especially the cerebral cortex, induced in rats by radiation. II. Some mechanisms of the malformations of the cortex.
J Comp Neurol. 1959 Dec;113:435-69. doi: 10.1002/cne.901130306.
4
Effects of prenatal x-irradiation on activity, emotionally, and maze-learning ability in the rat.
Radiat Res. 1962 Apr;16:441-52.
5
The histogenesis of the mouse cerebellum as studied by its tritiated thymidine uptake.
J Comp Neurol. 1960 Apr;114:137-59. doi: 10.1002/cne.901140204.
6
Activity and emotionality in pre- and neonatally x-irradiated rats.
J Comp Physiol Psychol. 1958 Oct;51(5):541-5. doi: 10.1037/h0045728.
7
Locomotor coordination following pre- and neonatal x-irradiation.
J Comp Physiol Psychol. 1958 Jun;51(3):292-4. doi: 10.1037/h0048135.
8
H3-thymidine autoradiographic studies on the cell proliferation and differentiation in the external and the internal granular layers of the mouse cerebellum.
J Comp Neurol. 1966 Oct;128(2):191-208. doi: 10.1002/cne.901280206.
9
Time of neuron origin in the hippocampal region. An autoradiographic study in the mouse.
Exp Neurol Suppl. 1965 Oct:Suppl 2:1-70.
10
Autoradiographic and histological studies of postnatal neurogenesis. 3. Dating the time of production and onset of differentiation of cerebellar microneurons in rats.
J Comp Neurol. 1969 Jul;136(3):269-93. doi: 10.1002/cne.901360303.
Zotero 插件