Wepler R, Rommel K
J Clin Chem Clin Biochem. 1978 Oct;16(10):543-5.
LP-X was investigated in the serum of 221 patients with and without cholestasis. The diagnostic sensitivity and the diagnostic specificity of the test were 0.9 and 0.88, respectively. When this test is used on a non-selected collective, however, the predictive value of the positive test is very low, whereas negative results have a high diagnostic value. Thus, in practice, LP-X is more suitable for the exclusion, rather than the detection of cholestasis.
对221例有或无胆汁淤积的患者血清进行了LP-X检测。该检测的诊断敏感性和诊断特异性分别为0.9和0.88。然而，当在未经过选择的人群中使用该检测时，阳性检测结果的预测价值非常低，而阴性结果具有较高的诊断价值。因此，在实际应用中，LP-X更适合用于排除胆汁淤积，而非检测胆汁淤积。
