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[埃因霍温地区0至5岁儿童的弯曲杆菌肠炎——一项流行病学研究]

[Campylobacter enteritis in 0-5-year-old children in the Eindhoven area - and epidemiological study].

作者信息

Van Lier J A, Haverkorn M J, Waelkens J J

出版信息

Tijdschr Kindergeneeskd. 1982 Apr;50(2):40-5.

PMID:7123534
Abstract

In the region Eindhoven 36 children with Campylobacter-enteritis were examined from I January 1980 to 31 December 1980. Symptoms were studied and stools were cultured over a four-month period. Abdominal pain and/or diarrhea occurred in more than 90% of patients and were not infrequently of longer duration. Bloody stools were found in 58% of patients and disappeared relatively early during the time of illness, as well as fever and vomiting. After one month Campylobacter could only be cultured in 5% of children; 14 household contacts, who proved to have Campylobacter-enteritis, had also negative stool cultures after one month. Asymptomatic carriership was found in four cases among these household contracts. Campylobacter fetus subspecies jejuni could not be isolated in stools of a number of asymptomatic individuals, working in the meat industry, who were considered to have a higher risk of infection. This group could therefore not be determined as an endogenous human reservoir. On the other hand Campylobacter was isolated in a few domestic animals without symptoms of illness, as well as in some cattle stables and sites. In these places, where several contaminated animals are together, significant reservoirs for human infection may be present.

摘要

1980年1月1日至1980年12月31日期间,在埃因霍温地区对36名弯曲杆菌肠炎患儿进行了检查。在四个月的时间里研究了症状并对粪便进行了培养。超过90%的患者出现腹痛和/或腹泻,且持续时间往往较长。58%的患者出现血便,在患病期间相对较早消失,发热和呕吐症状也是如此。一个月后,只有5%的儿童粪便中能培养出弯曲杆菌;14名被证实患有弯曲杆菌肠炎的家庭接触者,一个月后粪便培养结果也呈阴性。在这些家庭接触者中有4例发现无症状带菌者。在一些肉类行业工作的无症状个体粪便中未分离出空肠弯曲菌胎儿亚种,这些个体被认为感染风险较高。因此,这一群体不能被确定为人类内源性储存宿主。另一方面,在一些没有疾病症状的家畜以及一些牛舍和场地中分离出了弯曲杆菌。在这些有几只受污染动物聚集的地方,可能存在人类感染的重要储存宿主。

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