Chen K T, Arhelger R B, Flam M S, Hanson J H
Urology. 1982 Sep;20(3):316-9. doi: 10.1016/0090-4295(82)90652-5.
A case of biphasic malignant mesothelioma of the tunica vaginalis occurring in a sixty-four-year-old man is described. The tumor metastasized widely and led to the patient's death two and one-half years after diagnosis. Review of the literature revealed 7 cases of malignant mesothelioma of tunica vaginalis. These tumors appeared highly aggressive with early onset of metastasis. Histologically, the tumors may be epithelial, fibrous, or biphasic. In contrast to the benign variants of mesotheliomas, these tumors often show significant nuclear atypia, mitotic activity, and invasion of the epididymis, spermatic cord, lymphatic spaces, or the fibrous tissue of the tunica.
本文描述了一例发生在一名64岁男性的鞘膜双向性恶性间皮瘤。肿瘤广泛转移，在诊断后两年半导致患者死亡。文献回顾发现7例鞘膜恶性间皮瘤。这些肿瘤表现出高度侵袭性，转移出现较早。组织学上，肿瘤可能是上皮样、纤维样或双向性的。与间皮瘤的良性变体不同，这些肿瘤常表现出明显的核异型性、有丝分裂活性以及对附睾、精索、淋巴管间隙或鞘膜纤维组织的侵犯。
