Miller J K, Blewett D A, Buxton D
Vet Rec. 1982 Aug 7;111(6):124-6. doi: 10.1136/vr.111.6.124.
Thirty-five Scottish blackface gimmers in mid or late pregnancy were infected with Toxoplasma gondii by subcutaneous injection of 2000 tissue cysts. Approximately half the gimmers developed a mild febrile response between eight and 10 days after infection but were otherwise unaffected until lambing. Only seven gimmers lambed without loss; in the remainder abortions and neonatal deaths accounted for 27 of the 31 lambs born. These losses occurred predominantly among gimmers which had been infected in mid pregnancy. Antibody titres in the toxoplasma indirect haemagglutination test rose sharply after the 10th day post infection and remained high for over 200 days. The majority of abortions and neonatal deaths occurred after the 40th day post infection by which time mean indirect haemagglutination titres had exceeded 1/320.
对35只妊娠中期或晚期的苏格兰黑脸母羊通过皮下注射2000个组织包囊感染刚地弓形虫。大约一半的母羊在感染后8至10天出现轻微发热反应，但在产羔前没有其他不良反应。只有7只母羊顺利产羔无损失；其余母羊所产的31只羔羊中，有27只发生流产和新生羔羊死亡。这些损失主要发生在妊娠中期感染的母羊中。感染后第10天，弓形虫间接血凝试验中的抗体滴度急剧上升，并在200多天内一直保持在高水平。大多数流产和新生羔羊死亡发生在感染后第40天之后，此时间接血凝平均滴度已超过1/320。
