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[图宾根卫生研究所甲型肝炎病毒诊断结果]

[Results from the hepatitis A-virus diagnostic of the hygiene-institut in Tübingen].

作者信息

Flehmig B, Vallbracht A, Luthardt T, Gerth H J

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 Jun;252(2):147-53.

PMID:7124159
Abstract

The age-specific and seasonal distribution of serologically confirmed hepatitis A-cases in the area of Tübingen in southern Germany is reported. During 1978-1980 most of the hepatitis A-cases diagnosed by high anti-HAV-IgM titers occurred from September to December. The age distribution of patients with German names showed two age-related peaks, the first one in young children 5-10 years of age and a second one in young adults between 20-30 years. In patients with names suggesting mediterranean origin there is only one age-related peak in early childhood. A comparison of German children with children of foreign parents born and grown up in Germany shows an earlier infection and higher infection rate in the latter. The parents of these children are almost exclusively immigrant workers from mediterranean countries. Visits of the children to the home countries of their parents in which hepatitis A is very common are supposed to be of prime importance for the high prevalence and early occurrence of hepatitis A in this group.

摘要

报告了德国南部图宾根地区血清学确诊甲型肝炎病例的年龄特异性和季节性分布情况。在1978 - 1980年期间,通过高抗甲型肝炎病毒免疫球蛋白M滴度诊断出的大多数甲型肝炎病例发生在9月至12月。有德国名字的患者年龄分布显示出两个与年龄相关的高峰,第一个高峰在5 - 10岁的幼儿中,第二个高峰在20 - 30岁的年轻人中。有暗示地中海血统名字的患者在幼儿期只有一个与年龄相关的高峰。将德国儿童与在德国出生和长大的外籍父母的孩子进行比较,结果显示后者感染更早且感染率更高。这些孩子的父母几乎都是来自地中海国家的移民工人。孩子们前往甲型肝炎非常常见的父母原籍国探亲被认为是该群体中甲型肝炎高患病率和早期发病的主要原因。

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