蛛网膜下腔出血患者心电图异常及心肌特异性酶的研究

A study of ECG abnormalities and myocardial specific enzymes in patients with subarachnoid haemorrhage.

作者信息

Rudehill A, Gordon E, Sundqvist K, Sylvén C, Wahlgren N G

出版信息

Acta Anaesthesiol Scand. 1982 Aug;26(4):344-50. doi: 10.1111/j.1399-6576.1982.tb01779.x.

DOI:10.1111/j.1399-6576.1982.tb01779.x

Abstract

Twenty-two patients with subarachnoid haemorrhage were investigated for changes in myoglobin, total CK, CK-MB and CK-BB in serum and for the incidence of ECG abnormalities. Serial ECG's showed abnormalities in 20 patients; 15 of these had T wave changes, 15 Q-Tc prolongation, ten had S-T depression and nine U waves and in seven cases arrhythmias were found. The purpose of the study was to find out whether a relationship could be established between the ECG abnormalities and changes in serum myoglobin and enzymes. However, in no patient could myoglobin or enzyme patterns consistent with acute myocardial or cerebral damage be observed and therefore the ECG abnormalities do not seem to be related to detectable myocardial damage.

摘要

对22例蛛网膜下腔出血患者进行了血清肌红蛋白、总肌酸激酶（CK）、肌酸激酶同工酶MB（CK-MB）和肌酸激酶同工酶BB（CK-BB）变化以及心电图异常发生率的研究。系列心电图显示20例患者存在异常；其中15例有T波改变，15例QTc延长，10例ST段压低，9例出现U波，7例发现心律失常。本研究的目的是确定心电图异常与血清肌红蛋白和酶变化之间是否能建立联系。然而，在任何患者中均未观察到与急性心肌或脑损伤一致的肌红蛋白或酶模式，因此心电图异常似乎与可检测到的心肌损伤无关。