Lang P, Chipman C W, Siden H, Williams R G, Norwood W I, Castaneda A R
Am J Cardiol. 1982 Oct;50(4):795-9. doi: 10.1016/0002-9149(82)91236-x.
Hemodynamic data obtained in the intensive care unit, immediately after repair of tetralogy of Fallot, were compared with measurements obtained at 1 year postoperative catheterization in 98 infants and children. Eight of 12 patients who had pulmonary artery oxygen saturation of 80% or greater in the intensive care unit had a pulmonary to systemic flow ratio greater than 1.5 at catheterization; all 79 patients who had a pulmonary artery oxygen saturation of ess than 80% in the intensive care unit had a pulmonary to systemic flow ratio of 1.5 or less at catheterization. Five of six patients who had a right ventricular outflow tract pressure gradient greater than 40 mm Hg in the intensive care unit had a gradient greater than 40 mm Hg at catheterization; 7 of 61 patients who had a right ventricular outflow tract gradient of 40 mm Hg or less in the intensive care unit had a gradient greater than 40 mm Hg at catheterization. The addition of measurements of right ventricular pressure and the right ventricular to systemic arterial pressure ratio in the intensive care unit did not improve sensitivity in identifying patients with a right ventricular outflow tract gradient greater than 40 mm Hg at catheterization. Intensive care unit measurement of pulmonary artery oxygen saturation is valuable for determining the presence or absence of a significant left to right shunt after repair of tetralogy of Fallot and should be considered an adjunct to patient management. Intensive care unit measurement of the right ventricular outflow tract gradient identifies patients with a significant right ventricular outflow tract gradient at catheterization but is not highly sensitive.
对98例婴幼儿和儿童法洛四联症修复术后立即在重症监护病房获得的血流动力学数据,与术后1年导管检查时获得的测量值进行了比较。在重症监护病房肺动脉血氧饱和度达到或超过80%的12例患者中,有8例在导管检查时肺循环与体循环血流量之比大于1.5;在重症监护病房肺动脉血氧饱和度低于80%的所有79例患者,在导管检查时肺循环与体循环血流量之比为1.5或更低。在重症监护病房右心室流出道压力阶差大于40 mmHg的6例患者中,有5例在导管检查时阶差大于40 mmHg;在重症监护病房右心室流出道阶差为40 mmHg或更低的61例患者中,有7例在导管检查时阶差大于40 mmHg。在重症监护病房增加右心室压力及右心室与体循环动脉压力比值的测量,对于识别导管检查时右心室流出道阶差大于40 mmHg的患者,并没有提高其敏感性。重症监护病房测量肺动脉血氧饱和度,对于确定法洛四联症修复术后是否存在明显的左向右分流很有价值,应被视为患者管理的辅助手段。重症监护病房测量右心室流出道阶差可识别导管检查时有明显右心室流出道阶差的患者,但敏感性不高。