Correa-Oliveira R, Mota-Santos T A, Gazzinelli G
Am J Trop Med Hyg. 1982 Sep;31(5):991-8. doi: 10.4269/ajtmh.1982.31.991.
Mechanically transformed schistosomula of Schistosoma mansoni exposed to mouse, rat or human inactivated immune sera (coated schistosomula) and then injected intravenously into CBA mice were recovered from their lungs in smaller numbers than were schistosomula exposed to normal sera, immune sera absorbed with S. mansoni tegument, or sera from mice bearing unisexual cercarial infections and displaying moderate titers of lethal antibodies. The reduction of the number of coated schistosomula recovered from the lungs, as well as the lethal effect in vitro, were mediated by 7S fraction of the immune sera. Decomplementation (by Cobra Venom Factor) or irradiation (650 R, 1, 3, and 5 days before injection) of recipient mice, increased the number of coated schistosomula recovered from their lungs.
曼氏血吸虫机械转化的童虫暴露于小鼠、大鼠或人的灭活免疫血清（包被童虫），然后静脉注射到CBA小鼠体内，从其肺中回收的数量比暴露于正常血清、用曼氏血吸虫体表吸收的免疫血清或来自感染单性尾蚴并显示中等致死抗体滴度的小鼠血清中的童虫数量少。从肺中回收的包被童虫数量的减少以及体外致死效应是由免疫血清的7S组分介导的。对受体小鼠进行去补体（用眼镜蛇毒因子）或照射（注射前1、3和5天，650伦琴），可增加从其肺中回收的包被童虫数量。
