Brotman S, Browner B D, Cowley R A
Am Surg. 1982 Sep;48(9):484-6.
Judging the appropriate time for amputating lower extremities with open fractures and major soft tissue damage is a major problem for physicians. Limb salvage through vascular repair and external fixation is frequently unjustified. Attempts at saving a limb that should be amputated often are followed by renal failure, sepsis, and death. Much research remains to be done in this area.
判断开放性骨折并伴有严重软组织损伤的下肢截肢的合适时机，对医生来说是个大问题。通过血管修复和外固定来挽救肢体常常是不合理的。试图挽救本应截肢的肢体，往往会导致肾衰竭、败血症和死亡。这一领域仍有许多研究有待开展。
