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具有α-乳白蛋白样活性的附睾分泌蛋白与大鼠精子质膜的关联

Association of epididymal secretory proteins showing alpha-lactalbumin-like activity with the plasma membrane of rat spermatozoa.

作者信息

Jones R, Brown C R

出版信息

Biochem J. 1982 Jul 15;206(1):161-4. doi: 10.1042/bj2060161.

DOI:10.1042/bj2060161
PMID:7126189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1158563/
Abstract

Three hormonally regulated proteins with mol.wts of 18 500, 19 000 and 23 000 have been shown to associate with the plasma membrane of spermatozoa during maturation in the epididymis. All three proteins showed some alpha-lactalbumin-like activity, suggesting that they may act in concert with epididymal glycosidases and glycosyltransferases to regulate the modification of sugars on membrane-bound glycoproteins.

摘要

在附睾中成熟过程中,已证明三种分子量分别为18500、19000和23000的激素调节蛋白与精子的质膜相关联。所有这三种蛋白都表现出一些α-乳白蛋白样活性,这表明它们可能与附睾糖苷酶和糖基转移酶协同作用,以调节膜结合糖蛋白上糖的修饰。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/1158563/551626627d90/biochemj00369-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/1158563/551626627d90/biochemj00369-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/1158563/551626627d90/biochemj00369-0163-a.jpg

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Association of epididymal secretory proteins showing alpha-lactalbumin-like activity with the plasma membrane of rat spermatozoa.具有α-乳白蛋白样活性的附睾分泌蛋白与大鼠精子质膜的关联
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本文引用的文献

1
Androgenic regulation of messenger RNA in rat epididymis.雄激素对大鼠附睾中信使核糖核酸的调节作用。
Biochem J. 1980 Sep 15;190(3):505-12. doi: 10.1042/bj1900505.
2
Hormonal regulation of protein synthesis in the rat epididymis. Characterization of androgen-dependent and testicular fluid-dependent proteins.大鼠附睾中蛋白质合成的激素调节。雄激素依赖性和睾丸液依赖性蛋白质的特性。
Biochem J. 1980 Jun 15;188(3):667-76. doi: 10.1042/bj1880667.
3
Labeling of lymphocyte surface antigens by the lipophilic, photoactivatable reagent hexanoyldiiodo-N-(4-azido-2-nitrophenyl)tyramine.
用亲脂性、光可活化试剂己酰二碘 -N-(4-叠氮基-2-硝基苯基)酪胺标记淋巴细胞表面抗原。
Biochemistry. 1980 Jun 24;19(13):3092-9. doi: 10.1021/bi00554a040.
4
Labelling of membrane glycoproteins on rat spermatozoa collected from different regions of the epididymis.对从附睾不同区域采集的大鼠精子上膜糖蛋白的标记。
Biochem J. 1981 Nov 15;200(2):457-60. doi: 10.1042/bj2000457.
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Teratocarcinoma antigen is secreted by epididymal cells and coupled to maturing sperm.
Exp Cell Res. 1982 Feb;137(2):485-8. doi: 10.1016/0014-4827(82)90058-1.
6
A 28K-dalton cell surface autoantigen of spermatogenesis: characterization using a monoclonal antibody.一种精子发生过程中的28千道尔顿细胞表面自身抗原:利用单克隆抗体进行的特性鉴定
Dev Biol. 1982 Jan;89(1):92-100. doi: 10.1016/0012-1606(82)90297-4.
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Antibody to a sperm surface glycoprotein inhibits the egg jelly-induced acrosome reaction of sea urchin sperm.针对精子表面糖蛋白的抗体可抑制海胆精子的卵胶诱导的顶体反应。
Dev Biol. 1980 Oct;79(2):325-33. doi: 10.1016/0012-1606(80)90119-0.
8
Evidence for alpha-lactalbumin-like activity in reproductive tract fluids of the male rat.雄性大鼠生殖道液中存在α-乳白蛋白样活性的证据。
Biol Reprod. 1981 Sep;25(2):385-92. doi: 10.1095/biolreprod25.2.385.
9
UDP-galactose:N-acetylglucosamine galactosyltransferase in fluids from rat rete testis and epididymis.
Biol Reprod. 1980 Sep;23(2):377-85. doi: 10.1095/biolreprod23.2.377.
10
Characterization of hormonally regulated secretory proteins from the caput epididymidis of the rabbit.兔附睾头中激素调节分泌蛋白的特性分析
Biochem J. 1981 Apr 15;196(1):105-14. doi: 10.1042/bj1960105.