[在强磁场中用胰蛋白酶水解球状蛋白质]

[Hydrolysis of globular proteins with trypsin in a strong magnetic field].

作者信息

Nazarova N M, Livshits V A, Anzin V B, Veselago V G, Kuznetsov A N

出版信息

Biofizika. 1982 Jul-Aug;27(4):720-1.

Abstract

To test probable effect of the magnetic field (MF) on the dynamic structure of globular proteins the action of strong MF on proteolysis rate of methemoglobin and serum albumin with trypsin was studied. It has been found that the MF up to 10 T does not affect the proteolysis rate of these proteins and does not effect that of serum albumin with immobilized trypsin. This makes impossible consideration of the effect on the dynamic structure of globular proteins as a mechanism of the MF action on biological systems.

摘要

为了测试磁场（MF）对球状蛋白质动态结构的可能影响，研究了强磁场对高铁血红蛋白和血清白蛋白与胰蛋白酶的蛋白水解速率的作用。已发现高达10特斯拉的磁场不会影响这些蛋白质的蛋白水解速率，也不会影响固定化胰蛋白酶对血清白蛋白的蛋白水解速率。这使得将对球状蛋白质动态结构的影响视为磁场作用于生物系统的机制变得不可能。