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[禁食和肌肉运动时大鼠肝脏与心脏中胰岛素依赖性细胞质调节因子活性]

[Insulin-dependent cytoplasmic regulator activity in the rat liver and heart in fasting and muscle work].

作者信息

Gaĭnutdinov M Kh, Abibova E B, Gizatulina Z Z, Turakulov Ia Kh

出版信息

Biull Eksp Biol Med. 1982 Jul;94(7):37-40.

PMID:7126823
Abstract

Upon starving and muscle work the activity of an insulin-dependent cytoplasmic regulator (IDR) in the rat liver has been demonstrated to be lowered. This is one of the mechanisms of glycogenolysis and gluconeogenesis stimulation. Rapid increase in IDR activity in the heart and liver has been recorded in the period of recovery after swimming, with the increase being more intense in the heart. It has been shown that in the heart the resynthesis of glycogen proceeds more rapidly than in the liver. Therefore, the rate of glycogen resynthesis by the liver and heart correlates with IDR activity.

摘要

在饥饿和肌肉运动时,已证明大鼠肝脏中胰岛素依赖性细胞质调节因子(IDR)的活性会降低。这是糖原分解和糖异生刺激的机制之一。在游泳后的恢复阶段,已记录到心脏和肝脏中IDR活性迅速增加,且心脏中的增加更为强烈。研究表明,心脏中糖原的再合成比肝脏中进行得更快。因此,肝脏和心脏中糖原再合成的速率与IDR活性相关。

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