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[大鼠下颌下腺损伤后血清分析]

[Analysis of the blood serum after an injury to the rat submandibular gland].

作者信息

Belopol'skiĭ A A, Denisov A B, Pomerantseva E N

出版信息

Biull Eksp Biol Med. 1982 Aug;94(8):108-10.

PMID:7126839
Abstract

Experiments on Wistar rats were carried out to examine the changes in protein, glycoprotein, enzymatic and antigenic blood content after sialotomy of the salivary gland with an object of detecting mitogens. It was demonstrated that injury is accompanied by a moderately pronounced dysproteinemia, an increase in the seromucoid fraction, 48 hours after injury, and by variation in the ratio of LDH isozyme fractions, characteristic of the anaerobic metabolic pattern. No antigens of the injured gland were seen in the blood. The evidence obtained does not confirm the participation of high-molecular proteins of the injured gland in the activation of distant proliferation in the corneal epithelium.

摘要

对Wistar大鼠进行实验,以检测唾液腺切开术后血液中蛋白质、糖蛋白、酶和抗原含量的变化,目的是检测有丝分裂原。结果表明,损伤伴随着中度明显的蛋白血症、损伤后48小时血清类粘蛋白分数增加以及乳酸脱氢酶同工酶分数比例的变化,这是无氧代谢模式的特征。血液中未发现受损腺体的抗原。所获得的证据不支持受损腺体的高分子蛋白质参与角膜上皮远距离增殖的激活。

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