Aleksanian Iu T, Ignatova T N
Biull Eksp Biol Med. 1982 Aug;94(8):77-9.
Hybrids of cultivated mouse hepatoma XXIIA cells were studied for the presence of species-specificity antigens. Forssman antigen, and antigen similar to human B-isoantigen. The cells of MGXXIIA hepatoma, clone culture of L mouse fibroblasters and RJK hamster cells were used as parental cells. To obtain hybrids, use was made of whole hepatoma cells. Subject to study were 1 clone of microcellular intra-species, 2 whole cell clones and 2 clones of microcellular interspecies hepatoma hybrids. Antigens in hybrid cells were studied with the rapid cytotoxic test, cell agglutination and antibody absorption tests. Unlike cultivated mouse cells, only Forssman antigen was detected in cultivated hamster cells. Species-specificity antigens, Forssman antigen and antigen similar to human B-isoantigen were revealed in the cells of both the intraspecies and all interspecies hepatoma hybrids.
对培养的小鼠肝癌XXIIA细胞杂种进行了研究，以检测物种特异性抗原、福斯曼抗原以及与人B同种抗原相似的抗原。MGXXIIA肝癌细胞、L小鼠成纤维细胞的克隆培养物和RJK仓鼠细胞用作亲本细胞。为获得杂种细胞，使用了整个肝癌细胞。研究对象为1个种内微细胞克隆、2个全细胞克隆以及2个种间肝癌杂种微细胞克隆。通过快速细胞毒性试验、细胞凝集试验和抗体吸收试验对杂种细胞中的抗原进行了研究。与培养的小鼠细胞不同，在培养的仓鼠细胞中仅检测到福斯曼抗原。在种内和所有种间肝癌杂种细胞中均发现了物种特异性抗原、福斯曼抗原以及与人B同种抗原相似的抗原。
