Cappelaere P, Chauvergne J, Guerrin J
Bull Cancer. 1982;69(3):284-91.
The objective of medical treatment is to define the most active regimen and to combine them with optimal efficiency in the overall management of ovarian cancer patients, according to the results of surgical examination and the radiotherapeutic possibilities. The chemotherapy of common epithelial tumours is basically composed of alkylating agent, adriamycin, cis-platinum and hexamethylmelamine. The combination of these drugs leads to a high rate of surgically controlled tumor regressions and more complete responses, the only treatment which significantly increases survival. Results are less efficient for relapses or after failure of first line chemotherapy. The adjuvant chemotherapy of malignant germ cell tumours is used more and more often. The present indications of hormonotherapy are limited. Immunostimulant agents are being studied by several assays and preliminary results are interesting.
医学治疗的目标是根据手术检查结果和放射治疗的可能性，确定最有效的治疗方案，并以最佳效率将其结合用于卵巢癌患者的整体管理。常见上皮性肿瘤的化疗基本由烷基化剂、阿霉素、顺铂和六甲蜜胺组成。这些药物的联合使用导致手术控制的肿瘤退缩率很高，且反应更完全，这是唯一能显著提高生存率的治疗方法。对于复发或一线化疗失败后的情况，效果较差。恶性生殖细胞肿瘤的辅助化疗使用得越来越频繁。目前激素疗法的适应证有限。几种试验正在研究免疫刺激剂，初步结果令人感兴趣。
