Vedin J A, Kristianson J K, Wilhelmsson C E
Eur J Clin Pharmacol. 1982;23(1):43-7. doi: 10.1007/BF01061376.
Disappearance pharmacokinetics, pharmacodynamics and general tolerance of i.v. timolol were compared in 12 healthy volunteers and 10 patients with a definite or proven acute myocardial infarction. The drug was administered to the patients immediately on arrival at the hospital after a median delay time of 4 h. Tolerance to the injections was good in both volunteers and patients. The study revealed disappearance pharmacokinetics that were similar in volunteers and patients.
