Babb T L, Wilson C L, Crandall P H
Exp Brain Res. 1982;47(3):317-28. doi: 10.1007/BF00239351.
Twenty-two patients with psychomotor epilepsy were implanted with depth electrodes along the axis of the mesial temporal lobe to identify an operable unilateral epileptic focus. Neuronal and field potentials were recorded in response to diffuse retinal illumination and clear short-latency responses were found in parahippocampal gyrus. These visual afferents in the mesial temporal lobe are assumed to be both from subcortical and cortical visual areas. There was a clear asymmetry in the ventral trajectory of the geniculostriate pathway as evidenced by asymmetric neuronal and field potential responses to brief flashes in right vs. left hippocampal gyrus and confirmed by a corresponding partial visual field deficit following therapeutic anterior temporal lobectomy. These results demonstrate that there is a retinotopic organization of fibers in the human geniculostriate pathway and that this pathway may have considerable variability in the anterior and ventral course these fibers take through the temporal lobe. These findings adequately account for the presence of direct projections from geniculate to hippocampal cortex and for unexpected hemianopsias with standard resections of the temporal lobe when there is a deviant detour of the geniculostriate pathway.
22例精神运动性癫痫患者沿着内侧颞叶轴植入深度电极，以确定可手术的单侧癫痫病灶。记录了对弥漫性视网膜照明的神经元和场电位反应，在海马旁回发现了清晰的短潜伏期反应。内侧颞叶中的这些视觉传入神经被认为既来自皮质下视觉区域，也来自皮质视觉区域。膝状体纹状体通路腹侧轨迹存在明显不对称，右侧与左侧海马回对短暂闪光的神经元和场电位反应不对称证明了这一点，治疗性前颞叶切除术后相应的部分视野缺损也证实了这一点。这些结果表明，人类膝状体纹状体通路中存在纤维的视网膜拓扑组织，并且该通路在这些纤维穿过颞叶的前部和腹侧走行中可能具有相当大的变异性。这些发现充分解释了从膝状体到海马皮质的直接投射的存在，以及当膝状体纹状体通路出现异常迂回时，标准颞叶切除术出现意外偏盲的原因。
