Val'dman A V, Medvedev O S, Rozhanskaia N I
Fiziol Zh SSSR Im I M Sechenova. 1982 Aug;68(8):1091-5.
In Wistar rats, spontaneously hypertensive rats (SHR) and in rats with one-kidney Goldblatt hypertension, naloxone (0.1 and 1.0 mg/kg) evoked the 10 mm Hg increase of blood pressure in the two groups of hypertensive rats, did not change sensitivity of their baroreceptor reflex but facilitated the reflex in normotensive rats. A possible role of endogenous peptides in blood pressure control is discussed in relation to their ability to stimulate mu- and delta-opiate receptors.
在Wistar大鼠、自发性高血压大鼠（SHR）以及一侧肾性Goldblatt高血压大鼠中，纳洛酮（0.1毫克/千克和1.0毫克/千克）可使两组高血压大鼠的血压升高10毫米汞柱，并未改变其压力感受器反射的敏感性，但却增强了正常血压大鼠的该反射。结合内源性肽刺激μ和δ阿片受体的能力，讨论了其在血压控制中的可能作用。
