O'dea M J, Zincke H, Utz D C, Bernatz P E
J Urol. 1978 Nov;120(5):540-2. doi: 10.1016/s0022-5347(17)57264-x.
Between 1950 and 1970, 44 patients (2.5 per cent) with renal cell carcinoma and a solitary metastatic lesion were treated at our clinic. Generally, treatment was aggressive, involving nephrectomy and excision of the metastatic lesion when possible. Patients presenting with the primary and metastatic lesion at the same time did not do as well as patients who presented with metastasis after nephrectomy. An operation for the metastatic lesion seemed to offer the best results in patients who presented with the solitary metastatic lesion after nephrectomy. The prognosis was uniformly poor in patients presenting with the primary and secondary lesion together, regardless of the mode of therapy. However, an operation seemed to be better marginally and did produce an occasional long-term survival.
1950年至1970年间，我院收治了44例（2.5%）肾细胞癌伴孤立性转移病灶的患者。一般来说，治疗较为积极，尽可能进行肾切除术及转移病灶切除术。同时出现原发灶和转移灶的患者预后不如肾切除术后出现转移的患者。对于肾切除术后出现孤立性转移病灶的患者，转移病灶手术似乎能带来最佳疗效。对于同时出现原发灶和继发灶的患者，无论采用何种治疗方式，预后均较差。然而，手术在一定程度上似乎更好，偶尔也能带来长期生存。
