Ovarian cells participate in the formation of tubular structures in mouse/rat heterosexual gonadal cocultures: a direct demonstration by in situ hybridization.

In situ hybridization of a mouse-specific satellite DNA probe has been used to identify mouse cells in heterosexual reaggregates of rat ovarian and mouse testicular cells. It has been shown that rat ovarian cells cooperate in forming testis tubules. The significance of this is discussed in terms of H-Y antigen.