Goerg R
Fortschr Med. 1982 Aug 26;100(31-32):1472-3.
Lung resection may be followed by pulmonary hypertension leading to cardio-respiratory insufficiency. Therefore, pulmonary arterial pressure should be known before operation. To test the presence of pulmonary hypertension, results of lung function studies and right heart catheterization were compared in 100 patients with bronchogenic carcinoma. Mean pulmonary arterial pressure could be correlated with arterial partial pressures of oxygen and carbon dioxide as well as with total airway resistance and the Tiffeneau-test (FEV1/VC). A multiple regression analysis including 5 non hemodynamic variables, however, demonstrated a standard estimation error of mean pulmonary arterial pressure of 4.4 mmHg at rest and 8.0 mmHg during exercise thus proving that the multiple regression is of no clinical significance. Also by a discriminant analysis, patients could not be identified with clinically sufficient reliability as hemodynamically normal or pathological. Thus, right heart catheterization is an indispensable prerequisite to lung resection.
肺切除术后可能会出现肺动脉高压，进而导致心肺功能不全。因此，手术前应了解肺动脉压力。为了检测肺动脉高压的存在，对100例支气管肺癌患者的肺功能研究结果和右心导管检查结果进行了比较。平均肺动脉压与动脉血氧分压和二氧化碳分压、总气道阻力以及蒂芬诺试验（FEV1/VC）相关。然而，一项包含5个非血流动力学变量的多元回归分析表明，静息时平均肺动脉压的标准估计误差为4.4 mmHg，运动时为8.0 mmHg，因此证明该多元回归无临床意义。同样，通过判别分析，也无法以临床上足够的可靠性将患者区分为血流动力学正常或病理状态。因此，右心导管检查是肺切除不可或缺的前提条件。
