Konietzko N, Petro W, Brockmann M, Taube K, Heye M
Dtsch Med Wochenschr. 1986 Nov 28;111(48):1830-3. doi: 10.1055/s-2008-1068720.
In 227 patients with bronchial carcinoma whose forced expiratory volume was less than 2.5 l, measurements revealed a mild but significant rise in mean pulmonary arterial pressure at rest and on mild exercise (60 W). There was no clinically useful correlation between the degree of pulmonary hypertension and other measurable values, such as stage of the tumor or spirometric, whole-body plethysmographic, scintigraphic, electrocardiographic and blood-gas measurements. The degree of pre-operative pulmonary hypertension in 142 operated patients correlated with neither postoperative complications nor with post-operative mortality. Six months after lung resection there was a mild rise in pulmonary artery mean pressure among 30 patients, statistically significant only in those after pneumonectomy at rest. These results do not justify routine pre-operative right-heart catheterization. This should be reserved for patients with marginal ventilatory findings and cardiac risk factor.
在227例用力呼气量小于2.5升的支气管癌患者中，测量结果显示，静息和轻度运动（60瓦）时平均肺动脉压有轻度但显著升高。肺动脉高压程度与其他可测量值之间无临床有用的相关性，如肿瘤分期或肺量计、全身体积描记法、闪烁扫描法、心电图和血气测量值。142例接受手术患者的术前肺动脉高压程度与术后并发症及术后死亡率均无相关性。肺切除术后6个月，30例患者的肺动脉平均压有轻度升高，仅在全肺切除术后静息时的患者中具有统计学意义。这些结果并不支持常规术前右心导管检查。此项检查应仅用于通气功能临界且有心脏危险因素的患者。
